“It’s unfortunate biologically we have to sleep.”

Execute like there’s no tomorrow, strategize like there will be.

Look for new enabling technologies that create a wide gap between how things have been done and how they can be done.

Every single industry is going through a major business model and technology oriented disruption.

Innovation in tech favors the naive and the stubborn. If you are too rational you won’t tackle problems that others once failed at.

Tip: Take the stodgiest, oldest, slowest moving industry you can find. And build amazing software for it.

I’m certainly not into money and prestige. For me there is simply nothing more exciting than people involved in the creation of great products. That is what drives me.

Sometimes things are the way they are and can’t be changed, other times it’s because no one ever tried. Your job is to find the latter.

Do things that incumbents can’t or won’t do because it’s economically or technically infeasible.

If you’re waiting for encouragement from others, you’re doing it wrong. By the time people think an idea is good, it’s probably too late.

If every customer is using your product “correctly”, you’ll never learn anything interesting about what to do next.

The only barrier to entry you can create is to consistently build a great product.

My workday begins around 11 A.M., with a cup of black coffee in each hand. If I had more hands, there would be more coffee.

When you’re doing something you’re passionate about, stress becomes a featurenot a bug.

Entrepreneurship: 10% coach, 20% player, 30% cheerleader, 40% waterboy.

I think I’m the kind of person who would be very difficult to employ – I’m pretty annoying, but driven.

The best technology is aimed far enough in the future that it stands out, but close enough to the present that it blends in.

That is why, according to this newer psychology, Christianity has already fulfilled its biological mission, and it is impossible for the modern man to understand its original significance.

Biologically the species is the accumulation of the experiments of all its successful individuals since the beginning.

I have always had this basic biological question in terms of evolution, if the drive to evolution is to like survive.

Each child is biologically required to have a mother. Fatherhood is a well-regarded theory, but motherhood is a fact.

Electrons and possibly x-rays to be able to get the architecture of these molecules, the molecular structures themselves, of very complex biological systems. That’s the ultimate goal.

Think about the whole world of biological complex sciences. We still don’t understand the way a protein folds the way it does.

The history of making war with biological weapons begins in mythology, in ancient oral traditions that preserved records of actual events and ideas of the era before the invention of written histories.

Probably there is nothing in human nature more resonant with charges than the flow of energy between two biologically alike bodies, one of which has lain in amniotic bliss inside the other, one of which has labored to give birth to the other.