“It’s unfortunate biologically we have to sleep.”

I have a lot of faults. I often interrupt in meetings. I talk too loud. I talk too fast.

Go after the customers that are working in the future, but haven’t totally lost their minds.

The product that wins is the one that bridges customers to the future, not the one that requires a giant leap.

Focus too much on the near-term and you won’t get tomorrow’s customers, focus too much on the long-term and you won’t get today’s.

We’re enamored with the concept that there’s always a price. But sometimes, your goal is to build a great company, not sell it.

Execute like there’s no tomorrow, strategize like there will be.

Look for new enabling technologies that create a wide gap between how things have been done and how they can be done.

Every single industry is going through a major business model and technology oriented disruption.

Innovation in tech favors the naive and the stubborn. If you are too rational you won’t tackle problems that others once failed at.

Tip: Take the stodgiest, oldest, slowest moving industry you can find. And build amazing software for it.

I’m certainly not into money and prestige. For me there is simply nothing more exciting than people involved in the creation of great products. That is what drives me.

Sometimes things are the way they are and can’t be changed, other times it’s because no one ever tried. Your job is to find the latter.

Do things that incumbents can’t or won’t do because it’s economically or technically infeasible.

If you’re waiting for encouragement from others, you’re doing it wrong. By the time people think an idea is good, it’s probably too late.

If every customer is using your product “correctly”, you’ll never learn anything interesting about what to do next.

The only barrier to entry you can create is to consistently build a great product.

I think it’s tragic that we have this human capacity, which appears to be hardwired, or so the evolutionary biologists say, for collective joy. We have these techniques for generating it that go back thousands of years, and yet we tend not to use this.

The fictional treatment of biographical material – a treatment that for me is essential – is full of traps.

That is why, according to this newer psychology, Christianity has already fulfilled its biological mission, and it is impossible for the modern man to understand its original significance.

Biologically the species is the accumulation of the experiments of all its successful individuals since the beginning.

I have always had this basic biological question in terms of evolution, if the drive to evolution is to like survive.

Each child is biologically required to have a mother. Fatherhood is a well-regarded theory, but motherhood is a fact.

Electrons and possibly x-rays to be able to get the architecture of these molecules, the molecular structures themselves, of very complex biological systems. That’s the ultimate goal.

Think about the whole world of biological complex sciences. We still don’t understand the way a protein folds the way it does.