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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.

Francis Crick

A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
FRANCIS CRICK

Criticism Friendship Goodness Measurement Science Value
Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
FRANCIS CRICK

Believe Myself Structure
It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
FRANCIS CRICK

Generation Hard Nature Strike
If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
FRANCIS CRICK

Bad Evidence Foundation Goodness Legal Logic
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK

Appearance Nature Ourselves Security
Avoid the temptation to work so hard that there is no time left for serious thinking.
FRANCIS CRICK

Avoid Serious Temptation Thinking Time
You’re nothing but a pack of neurons.
FRANCIS CRICK

Existence Science Yourself
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK

Oneself Simplicity Thinking
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICK

Evidence Freedom Science System
Exact knowledge is the enemy of vitalism.
FRANCIS CRICK

Enemy Knowledge One Liner
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
FRANCIS CRICK

Biology Information Material Myself Science
There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
FRANCIS CRICK

Average Difficult Paper Reading Science Understand
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location
We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
FRANCIS CRICK

Human Kind Man Reproduction Run
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK

Biology Born Possible Reproduction Science
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
FRANCIS CRICK

Correction Group Place Reading Right Start

Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.

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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.

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