It is notoriously difficult to define the word living.
FRANCIS CRICKIt is notoriously difficult to define the word living.
FRANCIS CRICKProtein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
FRANCIS CRICKWe are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
FRANCIS CRICKA comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICKYou’re nothing but a pack of neurons.
FRANCIS CRICKAgain the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
FRANCIS CRICKFree will is located in or near the anterior cingulate sulcus.
FRANCIS CRICKA good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
FRANCIS CRICKIn the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
FRANCIS CRICKExact knowledge is the enemy of vitalism.
FRANCIS CRICKThe balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICKIt is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
FRANCIS CRICKSince I essentially knew nothing, I had an almost completely free choice.
FRANCIS CRICKIf the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
FRANCIS CRICKAn honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
FRANCIS CRICKIt has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
FRANCIS CRICK