A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICKA comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICKProtein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
FRANCIS CRICKThere is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
FRANCIS CRICKChristianity may be OK between consenting adults in private but should not be taught to young children.
FRANCIS CRICKFor simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICKThe ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICKMy own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure”.
FRANCIS CRICKIf, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
FRANCIS CRICKWe are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
FRANCIS CRICKIf revealed religions have revealed anything it is that they are usually wrong.
FRANCIS CRICKIt is notoriously difficult to define the word living.
FRANCIS CRICKEvolution is cleverer than you are.
FRANCIS CRICKIt would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICKA man who is right every time is not likely to do very much.
FRANCIS CRICKIt now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICKIt has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
FRANCIS CRICK