Avoid the temptation to work so hard that there is no time left for serious thinking.
FRANCIS CRICKBiologists must constantly keep in mind that what they see was not designed, but rather evolved.
More Francis Crick Quotes
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I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
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If revealed religions have revealed anything it is that they are usually wrong.
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Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
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It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
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Exact knowledge is the enemy of vitalism.
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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
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Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
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An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
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It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
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When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There’s something that might be called the ‘graduate student syndrome’; graduate students hardly believe they can make a discovery.
FRANCIS CRICK