Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
FRANCIS CRICKThe balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
More Francis Crick Quotes
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
FRANCIS CRICK -
It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
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We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK -
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK -
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
FRANCIS CRICK -
You’re nothing but a pack of neurons.
FRANCIS CRICK -
One of the most frightening things in the Western world, and in this country in particular, is the number of people who believe in things that are scientifically false. If someone tells me that the earth is less than 10,000 years old, in my opinion he should see a psychiatrist.
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In my experience most mathematicians are intellectually lazy.
FRANCIS CRICK -
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICK -
A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
FRANCIS CRICK -
Since I essentially knew nothing, I had an almost completely free choice.
FRANCIS CRICK -
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICK