A theory should not attempt to explain all the facts, because some of the facts are wrong.
FRANCIS CRICKIt is notoriously difficult to define the word living.
More Francis Crick Quotes
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It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
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It is notoriously difficult to define the word living.
FRANCIS CRICK -
We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
FRANCIS CRICK -
Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
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I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK -
A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
FRANCIS CRICK -
Since I essentially knew nothing, I had an almost completely free choice.
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Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
FRANCIS CRICK -
There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
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In my experience most mathematicians are intellectually lazy.
FRANCIS CRICK