The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
FRANCIS CRICKIt is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
More Francis Crick Quotes
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Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
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Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
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It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
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We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
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In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
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My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure”.
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Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
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It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
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God is a hacker, not an engineer.
FRANCIS CRICK