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Since I essentially knew nothing, I had an almost completely free choice.

Francis Crick

We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
FRANCIS CRICK

Experiment Myself Result Science Team Work
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK

Appearance Nature Ourselves Security
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
FRANCIS CRICK

Brain Complication Detail Essential Place See Understand Universe
Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
FRANCIS CRICK

Believe Earth Help Need. Mental Old
You’re nothing but a pack of neurons.
FRANCIS CRICK

Existence Science Yourself
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK

Agreement Comparison Measurement Production
I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
FRANCIS CRICK

Expression Motivational Myself Strong Work
Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
FRANCIS CRICK

Determination Listen Sound Structure Try
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location
Avoid the temptation to work so hard that there is no time left for serious thinking.
FRANCIS CRICK

Avoid Serious Temptation Thinking Time
Evolution is cleverer than you are.
FRANCIS CRICK

Clever Evolution Yourself
In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
FRANCIS CRICK

Biology Experience Experiment Intellectual Mathematics Negative Reading Strong
It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
FRANCIS CRICK

Generation Hard Nature Strike
When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There’s something that might be called the ‘graduate student syndrome’; graduate students hardly believe they can make a discovery.
FRANCIS CRICK

Believe Difficult Discover Hard Science Start Yourself
There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
FRANCIS CRICK

Brain Man Ourselves Science Study Universe
A theory should not attempt to explain all the facts, because some of the facts are wrong.
FRANCIS CRICK

Explanation Fact Theory Wrong

Since I essentially knew nothing, I had an almost completely free choice.

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Since I essentially knew nothing, I had an almost completely free choice.

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