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It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.

Francis Crick

It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
FRANCIS CRICK

Escape Eyes Notice Ourselves Possible Science
In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
FRANCIS CRICK

Body Death Education People Soul Time
Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
FRANCIS CRICK

Argument Experiment Impression Negative Possible
Evolution is cleverer than you are.
FRANCIS CRICK

Clever Evolution Yourself
A man who is right every time is not likely to do very much.
FRANCIS CRICK

Accomplishment Man Right Time
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICK

Evidence Freedom Science System
We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
FRANCIS CRICK

Experiment Myself Result Science Team Work
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK

Appearance Nature Ourselves Security
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICK

Detail Evidence Ideas Ourselves Science Type
Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
FRANCIS CRICK

Determination Listen Sound Structure Try
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK

Oneself Simplicity Thinking
Christianity may be OK between consenting adults in private but should not be taught to young children.
FRANCIS CRICK

Children Privacy Religion Teaching Young
Since I essentially knew nothing, I had an almost completely free choice.
FRANCIS CRICK

Freedom Myself
It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
FRANCIS CRICK

Drama Easy Enlightenment Experience Feeling Place
Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
FRANCIS CRICK

Life Science Understand
Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
FRANCIS CRICK

Education Learning People Research Work

It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.

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It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.

Related Topics

Popular Authors

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