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You can do reverse engineering, but you can’t do reverse hacking.

Francis Crick

The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICK

Evidence Freedom Science System
We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
FRANCIS CRICK

Experiment Myself Result Science Team Work
Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
FRANCIS CRICK

Believe Earth Help Need. Mental Old
An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
FRANCIS CRICK

Honesty Knowledge Life Man Miracle Satisfaction State
A theory should not attempt to explain all the facts, because some of the facts are wrong.
FRANCIS CRICK

Explanation Fact Theory Wrong
Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
FRANCIS CRICK

Life Science Understand
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
FRANCIS CRICK

Brain Complication Detail Essential Place See Understand Universe
It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
FRANCIS CRICK

Generation Hard Nature Strike
I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
FRANCIS CRICK

Expression Motivational Myself Strong Work
In my experience most mathematicians are intellectually lazy.
FRANCIS CRICK

Experience Intellectual Mathematics
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
FRANCIS CRICK

Biology Information Material Myself Science
You can do reverse engineering, but you can’t do reverse hacking.
FRANCIS CRICK

Professional Technology Yourself
My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure”.
FRANCIS CRICK

Function Prejudice Science Study Understand Yourself
The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
FRANCIS CRICK

Dangerous Death Fight Himself Ideas Thinking
Chance is the only source of true novelty.
FRANCIS CRICK

Chance Novel True
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK

Agreement Comparison Measurement Production

You can do reverse engineering, but you can’t do reverse hacking.

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You can do reverse engineering, but you can’t do reverse hacking.

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