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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.

Francis Crick

I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
FRANCIS CRICK

Expression Motivational Myself Strong Work
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK

Appearance Nature Ourselves Security
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICK

Evidence Freedom Science System
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK

Biology Born Possible Reproduction Science
One of the most frightening things in the Western world, and in this country in particular, is the number of people who believe in things that are scientifically false. If someone tells me that the earth is less than 10,000 years old, in my opinion he should see a psychiatrist.
FRANCIS CRICK

Country Earth Myself Opinion People Scare World
There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
FRANCIS CRICK

Brain Man Ourselves Science Study Universe
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location
It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
FRANCIS CRICK

Generation Hard Nature Strike
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
FRANCIS CRICK

Division Group Science
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK

Agreement Comparison Measurement Production
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICK

Detail Evidence Ideas Ourselves Science Type
It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
FRANCIS CRICK

Biology Code Direction Evidence Science
You’re nothing but a pack of neurons.
FRANCIS CRICK

Existence Science Yourself
It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
FRANCIS CRICK

Escape Eyes Notice Ourselves Possible Science
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
FRANCIS CRICK

Brain Complication Detail Essential Place See Understand Universe
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK

Oneself Simplicity Thinking

If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.

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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.

Related Topics

Popular Authors

More Francis Crick Quotes