“A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.”

Since I essentially knew nothing, I had an almost completely free choice.

Avoid the temptation to work so hard that there is no time left for serious thinking.

Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.

God is a hacker, not an engineer.

If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.

Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.

There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.

Evolution is cleverer than you are.

A theory should not attempt to explain all the facts, because some of the facts are wrong.

The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.

The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.

If revealed religions have revealed anything it is that they are usually wrong.

In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.

A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.

A man who is right every time is not likely to do very much.

We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.