It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICKIt now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
More Francis Crick Quotes
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The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
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In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
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A busy life is a wasted life.
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God is a hacker, not an engineer.
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Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
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It is notoriously difficult to define the word living.
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In my experience most mathematicians are intellectually lazy.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
FRANCIS CRICK -
Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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You can do reverse engineering, but you can’t do reverse hacking.
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK







