Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
FRANCIS CRICKIt now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
More Francis Crick Quotes
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A busy life is a wasted life.
FRANCIS CRICK -
A knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
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I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
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When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There’s something that might be called the ‘graduate student syndrome’; graduate students hardly believe they can make a discovery.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
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Avoid the temptation to work so hard that there is no time left for serious thinking.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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Evolution is cleverer than you are.
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A theory should not attempt to explain all the facts, because some of the facts are wrong.
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Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
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Since I essentially knew nothing, I had an almost completely free choice.
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
FRANCIS CRICK