Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
FRANCIS CRICKEvolution is cleverer than you are.
More Francis Crick Quotes
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
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My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure”.
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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
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An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
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A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
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When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There’s something that might be called the ‘graduate student syndrome’; graduate students hardly believe they can make a discovery.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
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Evolution is cleverer than you are.
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
FRANCIS CRICK