In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
FRANCIS CRICKA man who is right every time is not likely to do very much.
More Francis Crick Quotes
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
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Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
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Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
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It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
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An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
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The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure”.
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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
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Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
FRANCIS CRICK