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We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.

Francis Crick

For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK

Oneself Simplicity Thinking
An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
FRANCIS CRICK

Honesty Knowledge Life Man Miracle Satisfaction State
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
FRANCIS CRICK

Correction Group Place Reading Right Start
It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
FRANCIS CRICK

Generation Hard Nature Strike
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK

Agreement Comparison Measurement Production
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICK

Detail Evidence Ideas Ourselves Science Type
Christianity may be OK between consenting adults in private but should not be taught to young children.
FRANCIS CRICK

Children Privacy Religion Teaching Young
It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
FRANCIS CRICK

Drama Easy Enlightenment Experience Feeling Place
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK

Biology Born Possible Reproduction Science
We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
FRANCIS CRICK

Human Kind Man Reproduction Run
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICK

Biology Chemistry Explanation Fact Modern Movement
It is notoriously difficult to define the word living.
FRANCIS CRICK

Difficult Live World
It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
FRANCIS CRICK

Escape Eyes Notice Ourselves Possible Science
A man who is right every time is not likely to do very much.
FRANCIS CRICK

Accomplishment Man Right Time
Avoid the temptation to work so hard that there is no time left for serious thinking.
FRANCIS CRICK

Avoid Serious Temptation Thinking Time

We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.

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We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.

Related Topics

Popular Authors

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