A theory should not attempt to explain all the facts, because some of the facts are wrong.
FRANCIS CRICKFree will is located in or near the anterior cingulate sulcus.
More Francis Crick Quotes
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The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
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Since I essentially knew nothing, I had an almost completely free choice.
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
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Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
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Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
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Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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In my experience most mathematicians are intellectually lazy.
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You can do reverse engineering, but you can’t do reverse hacking.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK