For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICKOne of the most frightening things in the Western world, and in this country in particular, is the number of people who believe in things that are scientifically false. If someone tells me that the earth is less than 10,000 years old, in my opinion he should see a psychiatrist.
More Francis Crick Quotes
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Exact knowledge is the enemy of vitalism.
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Avoid the temptation to work so hard that there is no time left for serious thinking.
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There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
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Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
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When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There’s something that might be called the ‘graduate student syndrome’; graduate students hardly believe they can make a discovery.
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An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
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The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
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It is notoriously difficult to define the word living.
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Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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A busy life is a wasted life.
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I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
FRANCIS CRICK