Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
FRANCIS CRICKIt is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
More Francis Crick Quotes
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In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
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It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
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Since I essentially knew nothing, I had an almost completely free choice.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
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Exact knowledge is the enemy of vitalism.
FRANCIS CRICK -
Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
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You can do reverse engineering, but you can’t do reverse hacking.
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A knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
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The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
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Christianity may be OK between consenting adults in private but should not be taught to young children.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
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In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
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Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
FRANCIS CRICK







