For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICKIt is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
More Francis Crick Quotes
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It is notoriously difficult to define the word living.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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You can do reverse engineering, but you can’t do reverse hacking.
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An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
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Christianity may be OK between consenting adults in private but should not be taught to young children.
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I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
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Free will is located in or near the anterior cingulate sulcus.
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Chance is the only source of true novelty.
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Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
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In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
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The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
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The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICK