“I agree, the world would be a better place if doctors were less enthusiastic about adopting very new drugs.”

The placebo effect is one of the most fascinating things in the whole of medicine. It’s not just about taking a pill, and your performance and your pain getting better. It’s about our beliefs and expectations. It’s about the cultural meaning of a treatment.

I spend a lot of time talking to people who disagree with me – I would go so far as to say that it’s my favourite leisure activity.

Data is the fabric of the modern world: just like we walk down pavements, so we trace routes through data, and build knowledge and products out of it.

These corporations run our culture, and they riddle it with bullshit.

If I was writing a lifestyle book it would have the same advice on every page, and you’d know it all already.

I’ve detected myself using a new rule of thumb: if you don’t link to primary sources, I just don’t trust you.

The plural of anecdotes is not data

Eat lots of fruit and vegetables, and live your whole life in every way as well as you can: exercise regularly as part of your daily routine, avoid obesity, don’t drink too much, don’t smoke, and don’t get distracted from the real, basic, simple causes of ill health.

But as we will see, even these things are hard to do on your own, and in reality require wholesale social and political changes.

There is this peculiar blind spot in the culture of academic medicine around whether withholding trial results is research misconduct. People who work in any industry can reinforce each others’ ideas about what is okay.

One of the things I always found interesting is the same tricks are used to distort medicine in all of those domains.

I think you’ll find it’s a bit more complicated than that.

I think you’ll find it’s a bit more complicated than that.

Science has authority not because of white coats or titles, but because of precision and transparency: you explain your theory, set out your evidence, and reference the studies that support your case.

Teaching needs an ecosystem that supports evidence-based practice. It will need better systems to disseminate the results of research more widely, but also a better understanding of research, so that teachers can be critical consumers of evidence.

You cannot reason people out of a position that they did not reason themselves into.

America has the best doctors, the best nurses, the best hospitals, the best medical technology, the best medical breakthrough medicines in the world.

To me the analogy [to climate change] is… doctors worry a lot about cholesterol. And if you go to the doctor, and the doctor says “oh, your life would be happier if you ate a different diet and exercised” people pay no attention.

I have three older brothers, and each one of them has chosen one of my parents’ education. Two of them are actors, and the third is a doctor as my mother is.

As doctors, we are not trained to communicate and understand the power of our words as they relate to a patient’s ability and desire to survive.

Yes. I’m a doctor, an epidemiologist, and lots of my professional colleagues flip back and forth between industry and medical roles. I know them; they are not bad people. But it is possible for good people in bad systems to do things that inflict enormous harm.

I’ve never been front and centre as an iconic American character [like in Doctor Strange]. Day to day, you know you’re painting on a very big canvas.

The doctor that acts out of love doesn’t burn out. He or she may get tired physically, but not emotionally.

I’m a football coach. I’m not a doctor … They don’t call plays, I don’t do surgeries. We have a great deal here.