“Yes. I’m a doctor, an epidemiologist, and lots of my professional colleagues flip back and forth between industry and medical roles. I know them; they are not bad people. But it is possible for good people in bad systems to do things that inflict enormous harm.”

If I was writing a lifestyle book it would have the same advice on every page, and you’d know it all already.

I’ve detected myself using a new rule of thumb: if you don’t link to primary sources, I just don’t trust you.

The plural of anecdotes is not data

Eat lots of fruit and vegetables, and live your whole life in every way as well as you can: exercise regularly as part of your daily routine, avoid obesity, don’t drink too much, don’t smoke, and don’t get distracted from the real, basic, simple causes of ill health.

But as we will see, even these things are hard to do on your own, and in reality require wholesale social and political changes.

There is this peculiar blind spot in the culture of academic medicine around whether withholding trial results is research misconduct. People who work in any industry can reinforce each others’ ideas about what is okay.

I agree, the world would be a better place if doctors were less enthusiastic about adopting very new drugs.

One of the things I always found interesting is the same tricks are used to distort medicine in all of those domains.

I think you’ll find it’s a bit more complicated than that.

I think you’ll find it’s a bit more complicated than that.

Science has authority not because of white coats or titles, but because of precision and transparency: you explain your theory, set out your evidence, and reference the studies that support your case.

Teaching needs an ecosystem that supports evidence-based practice. It will need better systems to disseminate the results of research more widely, but also a better understanding of research, so that teachers can be critical consumers of evidence.

You cannot reason people out of a position that they did not reason themselves into.

There are many differences between medicine and teaching, but they have much in common. Both involve craft and personal expertise, learned through experience; but both can be informed by the experience of others.

Transparency and detail are everything in science.

As it is a major component of blood, water is vital for transporting oxygen to the brain. Heaven forbid that your blood should dry out.

A few years ago he had a big heart transplant in Chicago, a five-hour operation. It took the doctors four hours to get him on the operating table.

In the next few years I’d love to play a female version of Doctor Who. I know exactly how I would play her – she would be crafty in a clever kind of way.

I truly feel the best doctors are ones who are criticized by nurses, patients and family. They do not make excuses and learn from their mistakes.

A doctor once told me that with crying you aren’t sure what its derivation is. If someone comes at you with a knife, you don’t cry: you scream, you try to run. When it’s over and you’re OK, that’s when you cry.

I actually wanted to be a doctor. But doing all those horrid rat dissections made me faint. I studied science till the 12th standard and later took up commerce. I was planning to do chartered accountancy, but fate had something else in store for me.

There’s huge satisfaction in that, but I’ve got to credit all the doctors and trainers in Cleveland.

I told my wife I’m afraid to go back to the doctor because I’m afraid they’re going to look at you and say: ‘ma’am, just sell him for parts. It’s like that old car that as soon as you fix one thing, something else goes out on it.

You can’t be a doctor if you don’t know the entire parts of the body.