It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
FRANCIS CRICKBiologists must constantly keep in mind that what they see was not designed, but rather evolved.
More Francis Crick Quotes
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My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure”.
FRANCIS CRICK -
Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
FRANCIS CRICK -
God is a hacker, not an engineer.
FRANCIS CRICK -
Christianity may be OK between consenting adults in private but should not be taught to young children.
FRANCIS CRICK -
Avoid the temptation to work so hard that there is no time left for serious thinking.
FRANCIS CRICK -
Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
FRANCIS CRICK -
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK -
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
FRANCIS CRICK -
A theory should not attempt to explain all the facts, because some of the facts are wrong.
FRANCIS CRICK -
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK -
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICK -
Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
FRANCIS CRICK -
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK -
Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
FRANCIS CRICK -
Since I essentially knew nothing, I had an almost completely free choice.
FRANCIS CRICK