A busy life is a wasted life.
FRANCIS CRICKFor simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
More Francis Crick Quotes
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A knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
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It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
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It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
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In the fullness of time, educated people will believe there is no soul independent of the body, and hence no life after death.
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It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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A theory should not attempt to explain all the facts, because some of the facts are wrong.
FRANCIS CRICK -
In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
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My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure”.
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
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In my experience most mathematicians are intellectually lazy.
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Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
FRANCIS CRICK -
Since I essentially knew nothing, I had an almost completely free choice.
FRANCIS CRICK







