Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
FRANCIS CRICKHow is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
More Francis Crick Quotes
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Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
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Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
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It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
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A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK -
Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
FRANCIS CRICK -
You can do reverse engineering, but you can’t do reverse hacking.
FRANCIS CRICK -
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK -
God is a hacker, not an engineer.
FRANCIS CRICK -
Since I essentially knew nothing, I had an almost completely free choice.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
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In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
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Exact knowledge is the enemy of vitalism.
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The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
FRANCIS CRICK







