It is changes that are chiefly responsible for diseases, especially the greatest changes, the violent alterations both in the seasons and in other things. (:)…regimen and temperature, and one period of life to another.

HIPPOCRATES

Hippocrates on alteration

“It is changes that are chiefly responsible for diseases, especially the greatest changes, the violent alterations both in the seasons and in other things. (:)…regimen and temperature, and one period of life to another.”

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