Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
FRANCIS CRICKAvoid the temptation to work so hard that there is no time left for serious thinking.
More Francis Crick Quotes
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
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A theory should not attempt to explain all the facts, because some of the facts are wrong.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
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God is a hacker, not an engineer.
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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
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Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
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A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
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Since I essentially knew nothing, I had an almost completely free choice.
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Exact knowledge is the enemy of vitalism.
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A busy life is a wasted life.
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A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
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In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
FRANCIS CRICK