It is notoriously difficult to define the word living.
FRANCIS CRICKIn my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
More Francis Crick Quotes
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
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My own prejudices are exactly the opposite of the functionalists’: “If you want to understand function, study structure”.
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It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
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It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
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Chance is the only source of true novelty.
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Free will is located in or near the anterior cingulate sulcus.
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You can do reverse engineering, but you can’t do reverse hacking.
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There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
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Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
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It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
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Exact knowledge is the enemy of vitalism.
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A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
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A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
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God is a hacker, not an engineer.
FRANCIS CRICK