In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
FRANCIS CRICKI also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
More Francis Crick Quotes
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Avoid the temptation to work so hard that there is no time left for serious thinking.
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It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
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A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK -
Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
FRANCIS CRICK -
An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
FRANCIS CRICK -
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
FRANCIS CRICK -
The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
FRANCIS CRICK -
Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
FRANCIS CRICK -
There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
FRANCIS CRICK -
Free will is located in or near the anterior cingulate sulcus.
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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
FRANCIS CRICK