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Those who do not know the torment of the unknown cannot have the joy of discovery.

Claude Bernard

Everything is poisonous, nothing is poisonous, it is all a matter of dose.
CLAUDE BERNARD

Amount Poison Portion
Experiment is fundamentally only induced observation.
CLAUDE BERNARD

Experiment Fundamental Observation
Mediocre men often have the most acquired knowledge. It is in the darker. It is in the darker regions of science that great men are recognized; they are marked by ideas which light up phenomena hitherto obscure and carry science forward.
CLAUDE BERNARD

Average Darkness Greatness Knowledge Man Recognition Science
Our ideas are only intellectual instruments which we use to break into phenomena; we must change them when they have served their purpose, as we change a blunt lancet that we have used long enough.
CLAUDE BERNARD

Break Change Enough Ideas Instrument Intellectual Purpose
In science, the best precept is to alter and exchange our ideas as fast as science moves ahead.
CLAUDE BERNARD

Ahead exchange Fast Ideas Move Science
Feeling alone guides the mind.
CLAUDE BERNARD

Alone Feeling Guide Mindset
In the philosophic sense, observation shows and experiment teaches.
CLAUDE BERNARD

Experiment Observation Philosophy Teaching
We must never make experiments to confirm our ideas, but simply to control them.
CLAUDE BERNARD

Confirm Control Experiment Simplicity
In teaching man, experimental science results in lessening his pride more and more by proving to him every day that primary causes, like the objective reality of things, will be hidden from him forever and that he can only know relations.
CLAUDE BERNARD

Experiment Forever Man Reality Relation Science Teaching
Particular facts are never scientific; only generalization can establish science.
CLAUDE BERNARD

Establishment Fact General Science
Put off your imagination, as you put off your overcoat, when you enter the laboratory. Put it on again, as you put on your overcoat, when you leave.
CLAUDE BERNARD

Imagination Leaving Science Yourself
When entering on new ground we must not be afraid to express even risky ideas so as to stimulate research in all directions. As Priestley put it, we must not remain inactive through false modesty based on fear of being mistaken.
CLAUDE BERNARD

Afraid Direction Fear Ground Ideas Mistake Modesty Risk
We achieve more than we know. We know more than we understand. We understand more than we can explain.
CLAUDE BERNARD

Achievement Explanation Team Work Understand
The first requirement in using statistics is that the facts treated shall be reduced to comparable units.
CLAUDE BERNARD

Compare Requirement Statistics Treat
All the vital mechanisms, varied as they are, have only one object, that of preserving constant the conditions of life in the internal environment.
CLAUDE BERNARD

Condition Environment Object Oneself Preserve
We must keep our freedom of mind, and must believe that in nature what is absurd, according to our theories, is not always impossible.
CLAUDE BERNARD

Absurd Believe Freedom Impossible Mindset Nature

Those who do not know the torment of the unknown cannot have the joy of discovery.

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Those who do not know the torment of the unknown cannot have the joy of discovery.

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