“Well-observed facts, though brought to light by passing theories, will never die; they are the material on which alone the house of science will at last be built.”

If I had to define life in a single phrase, I should clearly express my thought of throwing into relief one characteristic which, in my opinion, sharply differentiates biological science. I should say: life is creation.

First causes are outside the realm of science.

The great experimental principle, then, is doubt, that philosophic doubt which leaves to the mind its freedom and initiative, and from which the virtues most valuable to investigators in physiology and medicine are derived.

A great discovery is a fact whose appearance in science gives rise to shining ideas, whose light dispels many obscurities and shows us new paths.

A discovery is generally an unforeseen relation not included in theory.

Particular facts are never scientific; only generalization can establish science.

Men who believe too firmly in their theories, do not believe enough in the theories of others. So these despisers of their fellows make experiments only to destroy a theory, instead of to seek the truth.

The true worth of an experimenter consists in his pursuing not only what he seeks in his experiment, but also what he did not seek.

The mental never influences the physical. It is always the physical that modifies the mental, and when we think that the mind is diseased, it is always an illusion.

Science increases our power in proportion as it lowers our pride.

When we meet a fact which contradicts a prevailing theory, we must accept the fact and abandon the theory, even when the theory is supported by great names and generally accepted.

The terrain is everything; the germ is nothing.

The joy of discovery is certainly the liveliest that the mind of man can ever feel.

The experimenter who does not know what he is looking for will not understand what he finds.

The better educated we are and the more acquired information we have, the better prepared shall we find our minds for making great and fruitful discoveries.

A man of science rises ever, in seeking truth; and if he never finds it in its wholeness, he discovers nevertheless very significant fragments; and these fragments of universal truth are precisely what constitutes science.

I built you a sandcastle because you’re a princess, but I tore it down because I’m a loser.

True intimacy is only build around the freedom to disagree.

The coolest toys don’t have to be bought; they can be built.

There’s been so much wealth built up that we really can feel spending for some time.

If women built the bridges or were meant to build the bridges, then they would have done it.

There is a built-in sense of indebtedness in the consciousness of man, an awareness of owing gratitude, or being caled upon at certain moments to reciprocate

She built her castle at rock bottom.

I built a kingdom out of heartache and it is glorious.