“I’m interested in the hope we invest in science, and the disappointment we can feel when science flattens, or ‘explains,’ the larger mysteries of religion.”

I work a lot in the summers. My family goes to Maine, where we have a little house. My wife’s a writer, too, and we can write for six hours a day and then play with the kids.

I’m an enormous fan of Thomas Bernhard’s books, and I like the relentless feeling in his work – the pursuit of darkness, the negative – and I think in some sense I’ve internalised that as what one is supposed to do.

A self needed to spill out sometimes, a body should show evidence of what the hell went on inside it.

The common, the quotidian, is so much more unyielding to me, really stubborn and hard to work with, and I like this because it makes me think and it makes me worry. I can’t just plunge my hand into the meat of it. I need new approaches.

You can test things out without terrible consequences. Or maybe the consequences are there, but they are deferred, buried, much harder to detect.

Sorry, I said to myself, wondering how many times in my marriage I’d said that, how many times I’d meant it, how many times Claire had actually believed it, and, most important, how many times the utterance had any impact whatsoever on our dispute. What a lovely chart one could draw of this word Sorry.

Fiction is too complicated and too elusive to break down into a set of tricks.

The context of what can be known establishes that love and indifference are forms of language, but the wise addition of punctuation allows us to believe that there are other harms – the dash gives the reader the clear signal they are coming.

A misspelled word is probably an alias for some desperate call for aid, which is bound to fail.

Eventually you stop paying attention to your own feelings when there’s nothing to be done about them.

My first book, ‘The Age of Wire and String,’ came out in 1995, and it was hardly reviewed at all.

To refrain from storytelling is perhaps one of the highest forms of respect we can pay. Those people, with no stories to circle them, can die without being misunderstood.

Among other things, autoimmune disorders are an induction into a world of unstable information and no reliable expertise.

I like big doses of grief when I read: Richard Yates, Flannery O’Connor, Kenzabaro Oe, Thomas Bernhard.

It’s lonely to listen to the pleasure of others, not that I’ve made a habit of that kind of eavesdropping. There’s joy and passion in the next room, in the next bed, but it’s not yours.

It amazes me that parents are allowed to raise kids. There’s so much power and often very little accountability.