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Since I essentially knew nothing, I had an almost completely free choice.

Francis Crick

It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
FRANCIS CRICK

Biology Information Material Myself Science
A busy life is a wasted life.
FRANCIS CRICK

Busy Life One Liner Wasted Time
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
FRANCIS CRICK

Correction Group Place Reading Right Start
Avoid the temptation to work so hard that there is no time left for serious thinking.
FRANCIS CRICK

Avoid Serious Temptation Thinking Time
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK

Oneself Simplicity Thinking
Chance is the only source of true novelty.
FRANCIS CRICK

Chance Novel True
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICK

Biology Chemistry Explanation Fact Modern Movement
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
FRANCIS CRICK

Brain Complication Detail Essential Place See Understand Universe
Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
FRANCIS CRICK

Argument Experiment Impression Negative Possible
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICK

Detail Evidence Ideas Ourselves Science Type
In my experience most mathematicians are intellectually lazy.
FRANCIS CRICK

Experience Intellectual Mathematics
God is a hacker, not an engineer.
FRANCIS CRICK

God One Liner Science
Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
FRANCIS CRICK

Education Learning People Research Work
A theory should not attempt to explain all the facts, because some of the facts are wrong.
FRANCIS CRICK

Explanation Fact Theory Wrong
When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There’s something that might be called the ‘graduate student syndrome’; graduate students hardly believe they can make a discovery.
FRANCIS CRICK

Believe Difficult Discover Hard Science Start Yourself
You’re nothing but a pack of neurons.
FRANCIS CRICK

Existence Science Yourself

Since I essentially knew nothing, I had an almost completely free choice.

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Since I essentially knew nothing, I had an almost completely free choice.

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