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Since I essentially knew nothing, I had an almost completely free choice.

Francis Crick

You can do reverse engineering, but you can’t do reverse hacking.
FRANCIS CRICK

Professional Technology Yourself
It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
FRANCIS CRICK

Drama Easy Enlightenment Experience Feeling Place
It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
FRANCIS CRICK

Brain Complication Detail Essential Place See Understand Universe
Anybody who believes that the earth is less than 10,000 years old needs psychiatric help.
FRANCIS CRICK

Believe Earth Help Need. Mental Old
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICK

Evidence Freedom Science System
In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
FRANCIS CRICK

Biology Experience Experiment Intellectual Mathematics Negative Reading Strong
It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
FRANCIS CRICK

Biology Code Direction Evidence Science
The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
FRANCIS CRICK

Dangerous Death Fight Himself Ideas Thinking
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK

Oneself Simplicity Thinking
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK

Agreement Comparison Measurement Production
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK

Appearance Nature Ourselves Security
Since I essentially knew nothing, I had an almost completely free choice.
FRANCIS CRICK

Freedom Myself
Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
FRANCIS CRICK

Life Science Understand
If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.
FRANCIS CRICK

Bad Evidence Foundation Goodness Legal Logic
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
FRANCIS CRICK

Correction Group Place Reading Right Start
In my experience most mathematicians are intellectually lazy.
FRANCIS CRICK

Experience Intellectual Mathematics

Since I essentially knew nothing, I had an almost completely free choice.

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Since I essentially knew nothing, I had an almost completely free choice.

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