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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.

Francis Crick

I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
FRANCIS CRICK

Expression Motivational Myself Strong Work
It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
FRANCIS CRICK

Biology Code Direction Evidence Science
Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
FRANCIS CRICK

Argument Experiment Impression Negative Possible
A man who is right every time is not likely to do very much.
FRANCIS CRICK

Accomplishment Man Right Time
The dangerous man is the one who has only one idea, because then he’ll fight and die for it.
FRANCIS CRICK

Dangerous Death Fight Himself Ideas Thinking
A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK

Agreement Comparison Measurement Production
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
FRANCIS CRICK

Division Group Science
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location
Almost all aspects of life are engineered at the molecular level, and without understanding molecules we can only have a very sketchy understanding of life itself.
FRANCIS CRICK

Life Science Understand
It is notoriously difficult to define the word living.
FRANCIS CRICK

Difficult Live World
A busy life is a wasted life.
FRANCIS CRICK

Busy Life One Liner Wasted Time
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK

Biology Born Possible Reproduction Science
We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
FRANCIS CRICK

Experiment Myself Result Science Team Work
A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
FRANCIS CRICK

Criticism Friendship Goodness Measurement Science Value
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICK

Detail Evidence Ideas Ourselves Science Type
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICK

Biology Chemistry Explanation Fact Modern Movement

For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.

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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.

Related Topics

Popular Authors

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