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It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.

Francis Crick

A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.
FRANCIS CRICK

Agreement Comparison Measurement Production
Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
FRANCIS CRICK

Action Biology Problem
There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
FRANCIS CRICK

Brain Man Ourselves Science Study Universe
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICK

Biology Chemistry Explanation Fact Modern Movement
It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
FRANCIS CRICK

Generation Hard Nature Strike
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
FRANCIS CRICK

Division Group Science
God is a hacker, not an engineer.
FRANCIS CRICK

God One Liner Science
When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There’s something that might be called the ‘graduate student syndrome’; graduate students hardly believe they can make a discovery.
FRANCIS CRICK

Believe Difficult Discover Hard Science Start Yourself
Avoid the temptation to work so hard that there is no time left for serious thinking.
FRANCIS CRICK

Avoid Serious Temptation Thinking Time
If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
FRANCIS CRICK

Correction Group Place Reading Right Start
Evolution is cleverer than you are.
FRANCIS CRICK

Clever Evolution Yourself
Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
FRANCIS CRICK

Determination Listen Sound Structure Try
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK

Biology Born Possible Reproduction Science
Exact knowledge is the enemy of vitalism.
FRANCIS CRICK

Enemy Knowledge One Liner
It seems likely that most if not all the genetic information in any organism is carried by nucleic acid – usually by DNA, although certain small viruses use RNA as their genetic material.
FRANCIS CRICK

Biology Information Material Myself Science
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location

It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.

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It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.

Related Topics

Popular Authors

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