A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICKAnybody who believes that the earth is less than 10,000 years old needs psychiatric help.
More Francis Crick Quotes
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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God is a hacker, not an engineer.
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Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
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When you start in science, you are brainwashed into believing how careful you must be, and how difficult it is to discover things. There’s something that might be called the ‘graduate student syndrome’; graduate students hardly believe they can make a discovery.
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A man who is right every time is not likely to do very much.
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It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.
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The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
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It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
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An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
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Protein synthesis is a central problem for the whole of biology, and that it is in all probability closely related to gene action.
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For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
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Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
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Avoid the temptation to work so hard that there is no time left for serious thinking.
FRANCIS CRICK