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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.

Francis Crick

It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
FRANCIS CRICK

Generation Hard Nature Strike
Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
FRANCIS CRICK

Believe Myself Structure
Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
FRANCIS CRICK

Education Learning People Research Work
Chance is the only source of true novelty.
FRANCIS CRICK

Chance Novel True
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location
In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.
FRANCIS CRICK

Biology Experience Experiment Intellectual Mathematics Negative Reading Strong
Exact knowledge is the enemy of vitalism.
FRANCIS CRICK

Enemy Knowledge One Liner
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK

Appearance Nature Ourselves Security
A good scientist values criticism almost higher than friendship: no, in science criticism is the height and measure of friendship.
FRANCIS CRICK

Criticism Friendship Goodness Measurement Science Value
If revealed religions have revealed anything it is that they are usually wrong.
FRANCIS CRICK

Religion Reveal Wrong
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICK

Evidence Freedom Science System
It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
FRANCIS CRICK

Escape Eyes Notice Ourselves Possible Science
Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
FRANCIS CRICK

Argument Experiment Impression Negative Possible
You can do reverse engineering, but you can’t do reverse hacking.
FRANCIS CRICK

Professional Technology Yourself
For simplicity one can think of the + class as having one extra base at some point or other in the genetic message and the – class as having one too few.
FRANCIS CRICK

Oneself Simplicity Thinking
I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
FRANCIS CRICK

Expression Motivational Myself Strong Work

If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.

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If the code does indeed have some logical foundation then it is legitimate to consider all the evidence, both good and bad, in any attempt to deduce it.

Related Topics

Popular Authors

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