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A theory should not attempt to explain all the facts, because some of the facts are wrong.

Francis Crick

It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK

Appearance Nature Ourselves Security
Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
FRANCIS CRICK

Believe Myself Structure
Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
FRANCIS CRICK

Education Learning People Research Work
How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
FRANCIS CRICK

Division Group Science
Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
FRANCIS CRICK

Determination Listen Sound Structure Try
You’re nothing but a pack of neurons.
FRANCIS CRICK

Existence Science Yourself
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICK

Biology Chemistry Explanation Fact Modern Movement
A man who is right every time is not likely to do very much.
FRANCIS CRICK

Accomplishment Man Right Time
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICK

Detail Evidence Ideas Ourselves Science Type
Biologists must constantly keep in mind that what they see was not designed, but rather evolved.
FRANCIS CRICK

Biology Design Evolution Mindset Science See
It is not easy to convey, unless one has experienced it, the dramatic feeling of sudden enlightenment that floods the mind when the right idea finally clinches into place.
FRANCIS CRICK

Drama Easy Enlightenment Experience Feeling Place
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK

Biology Born Possible Reproduction Science
A busy life is a wasted life.
FRANCIS CRICK

Busy Life One Liner Wasted Time
Chance is the only source of true novelty.
FRANCIS CRICK

Chance Novel True
The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
FRANCIS CRICK

Evidence Freedom Science System

A theory should not attempt to explain all the facts, because some of the facts are wrong.

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A theory should not attempt to explain all the facts, because some of the facts are wrong.

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