You can do reverse engineering, but you can’t do reverse hacking.
FRANCIS CRICKA knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
More Francis Crick Quotes
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God is a hacker, not an engineer.
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It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
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We have to take away from humans in the long run their reproductive autonomy as the only way to guarantee the advancement of mankind.
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I also suspect that many workers in this field [molecular biology] and related fields have been strongly motivated by the desire, rarely actually expressed, to refute vitalism.
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It is one of the more striking generalizations of biochemistry – which surprisingly is hardly ever mentioned in the biochemical textbooks – that the twenty amino acids and the four bases, are, with minor reservations, the same throughout Nature.
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The balance of evidence both from the cell-free system and from the study of mutation, suggests that this does not occur at random, and that triplets coding the same amino acid may well be rather similar.
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Exploratory research is really like working in a fog. You don’t know where you’re going. You’re just groping. Then people learn about it afterwards and think how straightforward it was.
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Since I essentially knew nothing, I had an almost completely free choice.
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It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
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If, for example, all the codons are triplets, then in addition to the correct reading of the message, there are two incorrect readings which we shall obtain if we do not start the grouping into sets of three at the right place.
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In my experience most mathematicians are intellectually lazy.
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We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.
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Free will is located in or near the anterior cingulate sulcus.
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It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.
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How is the base sequence, divided into codons? There is nothing in the backbone of the nucleic acid, which is perfectly regular, to show us how to group the bases into codons.
FRANCIS CRICK