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Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.

Francis Crick

Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.
FRANCIS CRICK

Determination Listen Sound Structure Try
Rather than believe that Watson and Crick made the DNA structure, I would rather stress that the structure made Watson and Crick.
FRANCIS CRICK

Believe Myself Structure
A theory should not attempt to explain all the facts, because some of the facts are wrong.
FRANCIS CRICK

Explanation Fact Theory Wrong
Chance is the only source of true novelty.
FRANCIS CRICK

Chance Novel True
It would appear that the number of nonsense triplets is rather low, since we only occasionally come across them. However this conclusion is less secure than our other deductions about the general nature of the genetic code.
FRANCIS CRICK

Appearance Nature Ourselves Security
If revealed religions have revealed anything it is that they are usually wrong.
FRANCIS CRICK

Religion Reveal Wrong
The ultimate aim of the modern movement in biology is in fact to explain all biology in terms of physics and chemistry.
FRANCIS CRICK

Biology Chemistry Explanation Fact Modern Movement
There is no form of prose more difficult to understand and more tedious to read than the average scientific paper.
FRANCIS CRICK

Average Difficult Paper Reading Science Understand
An honest man, armed with all the knowledge available to us now, could only state that in some sense, the origin of life appears at the moment to be almost a miracle, so many are the conditions which would have had to have been satisfied to get it going.
FRANCIS CRICK

Honesty Knowledge Life Man Miracle Satisfaction State
In my experience most mathematicians are intellectually lazy.
FRANCIS CRICK

Experience Intellectual Mathematics
It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.
FRANCIS CRICK

Biology Born Possible Reproduction Science
There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.
FRANCIS CRICK

Brain Man Ourselves Science Study Universe
A knowledge of the true age of the Earth and of the fossil record makes it impossible for any balanced intellect to believe in the literal truth of every part of the Bible in the way that fundamentalists do.
FRANCIS CRICK

Age Balance Earth Fundamental Impossible Intellectual Knowledge Record True
A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.
FRANCIS CRICK

Detail Evidence Ideas Ourselves Science Type
Free will is located in or near the anterior cingulate sulcus.
FRANCIS CRICK

Freedom Location
Again the message to experimentalists is: Be sensible but don’t be impressed too much by negative arguments. If at all possible, try it and see what turns up. Theorists almost always dislike this sort of approach.
FRANCIS CRICK

Argument Experiment Impression Negative Possible

Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.

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Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.

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