“Despite all our toil and progress, the art of medicine still falls somewhere between trout casting and spook writing.”

Prejudice is a raft onto which the shipwrecked mind clambers and paddles to safety.

The rule in the art world is: you cater to the masses or you kowtow to the elite; you can’t have both.

People’s sex habits are as well known in Hollywood as their political opinions, and much less criticized.

Bad writing is not easier than good writing. It’s just as hard to make a toilet seat as it is a castle window. Only the view is different.

I have known a number of Don Juans who were good studs and who cavorted between the sheets without a psychiatrist to guide them. But most of the busy love-makers I knew were looking for masculinity rather than practicing it. They were fellows of dubious lust.

I know that a man who shows me his wealth is like the beggar who shows me his poverty; they are both looking for alms from me, the rich man for the alms of my envy, the poor man for the alms of my guilt.

Socially, a journalist ranks somewhere between the madam of a whorehouse and a bartender. but spiritually he ranks with Galileo, for he knows the world is round.

Love is a hole in the heart.

Chicago is a sort of journalistic Yellowstone Park, offering haven to a last herd of fantastic bravos.

In moderating, not satisfying desires, lies peace.

I have usually forgotten those who have admired my work, and seldom anyone who disliked it. Obviously, this is because praise is never enough and censure always too much.

For many years Hollywood held this double lure for me, tremendous sums of money for work that required no more effort than a game of pinochle.

I see a lot of fog and a few lights. I like it when life’s hidden. It gives you a chance to imagine nice things, nicer than they are.

The movies are one of the bad habits that corrupted our century.Of their many sins, I offer as the worst their effect on the intellectual side of the nation. It is chiefly from that viewpoint I write of them.

The movies are an eruption of trash that has lamed the American mind and retarded Americans from becoming cultured people.

I have written a raucous valentine to a poet’s dream and agony.

Love is the medicine that saves from disease.

Unless we put medical freedom into the constitution the time will come when medicine will organize into an undercover dictatorship and force people who wish doctors and treatment of their own choice to submit to only what the dictating outfit offers.

The best doctors give the least medicines

We look at science as the ultimate answer for everything yet we are really messy organisms and when the two collide in the upper echelons of medicine you think science will prevail but it’s not always that way.

There is this peculiar blind spot in the culture of academic medicine around whether withholding trial results is research misconduct. People who work in any industry can reinforce each others’ ideas about what is okay.

One of the things I always found interesting is the same tricks are used to distort medicine in all of those domains.

There are many differences between medicine and teaching, but they have much in common. Both involve craft and personal expertise, learned through experience; but both can be informed by the experience of others.

Money brings you food, but not appetite; medicine, but not health; acquaintances, but not friends.