“Be as smart as you can, but remember that it is always better to be wise than to be smart.”

I don’t talk about my beliefs too much in public probably because I feel very strongly that it’s something personal – more than personal, it’s private.

The one hour live debate in the West Wing that we did was one of the most exciting times for me on stage or on camera, because anything could go wrong.

Never Have Your Dog Stuffed is really advice to myself, a reminder to myself not to avoid change or uncertainty, but to go with it, to surf into change.

For a while in my teens, I was sure I had it. It was about getting to heaven. If heaven existed and lasted forever, then a mere lifetime spent scrupulously following orders was a small investment for an infinite payoff.

I’ve been nominated twice before as actor in a leading part. Now I’m nominated as actor in a supporting part.

I’ve been lucky enough to live through all the things that are supposed to give meaning to our lives, like parenting, grandparenting, art, celebrity.

Loneliness is everything it’s cracked up to be.

If I don’t win, I’ll just wait until I’m nominated for being in the theater during the show. Do they have one like that?

I was brought up as a Catholic, and I’m no longer a Catholic.

Eventually, I found a radical way of thinking about listening. Real listening is a willingness to let the other person change you.

Working on The West Wing was similar in many ways to my experience on M*A*S*H, because you had people willing to work late at night to get it just right.

I’m not trying to create some impression about myself. That doesn’t interest me.

My relationship with science is as someone who’s curious and hungry to know, hungry to understand. So all I have to offer is my ignorance and my curiosity, which is a good combination, as long as they come together.

You wouldn’t want to be called a sell-out by selling a product.

You have to leave the city of your comfort and go into the wilderness of your intuition.

Everybody’s on their toes and focused on what we’re about to do, and then there’s this moment where you relax because you see that everybody is there to do the best that they can.