“A discovery is generally an unforeseen relation not included in theory.”

Mediocre men often have the most acquired knowledge. It is in the darker. It is in the darker regions of science that great men are recognized; they are marked by ideas which light up phenomena hitherto obscure and carry science forward.

Experiment is fundamentally only induced observation.

The science of life is a superb and dazzlingly lighted hall which may be reached only by passing through a long and ghastly kitchen.

Our ideas are only intellectual instruments which we use to break into phenomena; we must change them when they have served their purpose, as we change a blunt lancet that we have used long enough.

Now, a living organism is nothing but a wonderful machine endowed with the most marvellous properties and set going by means of the most complex and delicate mechanism.

The eloquence of a scientist is clarity; scientific truth is always more luminous when its beauty is unadorned than when it is tricked out in the embellishments with which our imagination would seek to clothe it.

In science, the best precept is to alter and exchange our ideas as fast as science moves ahead.

We must remain, in a word, in an intellectual disposition which seems paradoxical, but which, in my opinion, represents the true mind of the investigator. We must have a robust faith and yet not believe.

True science teaches us to doubt and, in ignorance, to refrain.

Those who do not know the torment of the unknown cannot have the joy of discovery.

The doubter is a true man of science: he doubts only himself and his interpretations, but he believes in science.

Obervation is a passive science, experimentation is an active science.

The investigator should have a robust faith – and yet not believe.

The fact that knowledge endlessly recedes as the investigator is about to grasp it is what constitutes at the same time his torment and happiness.

If I had to define life in a single phrase, I should clearly express my thought of throwing into relief one characteristic which, in my opinion, sharply differentiates biological science. I should say: life is creation.

First causes are outside the realm of science.

In the context of general relativity, space almost is a substance.

I believe that the general growth in large [financial] institutions have occurred in the context of an underlying structure of markets in which many of the larger risks are dramatically — I should say, fully — hedged.

But in fact as Secretary of Homeland Security General John Kelly acknowledged at his confirmation hearing, walls and barriers alone are insufficient to insure security.

The general tendency of things throughout the world is to render mediocrity the ascendant power among mankind.

But we will encourage the church to do that in general for anyone and everyone who’s seeking to be a mature believer in Christ.

When people are laughing, they’re generally not killing one another.

There is no ethics in general. There are only-eventually-ethics of processes by which we treat the possibilities of a situation.

I am in general a very pessimistic person with an optimistic, day to day take on things. The bare facts of life are utterly terrifying. And yet, one can laugh. Indeed, one has to laugh precisely because of the darkness: the nervous laughter of the trenches.