“It’s necessary to be slightly underemployed if you are to do something significant.”

You’ve never heard of an English lover. Only an English patient.

Already for thirty-five years he had not stopped talking and almost nothing of fundamental value had emerged.

The way to do great science is to stay away from subjects that are overpopulated, and go to the frontiers.

Some think there is something wrong about enhancing people.

The pace of discovery is going unbelievably fast.

No one may have the guts to say this, but if we could make better human beings by knowing how to add genes, why shouldn’t we?

The luckiest thing that ever happened to me was that my father didn’t believe in God, and so he had no hang-ups about souls.

Whenever you interview fat people, you feel bad, because you know you’re not going to hire them.

I think the reason people are dealing with science less well now than 50 years ago is that it has become so complicated.

No good model ever accounted for all the facts, since some data was bound to be misleading if not plain wrong.

One could not be a successful scientist without realizing that, in contrast to the popular conception supported by newspapers and mothers of scientists, a goodly number of scientists are not only narrow-minded and dull, but also just stupid.

If you succeed with your first dream, it helps. You know, people trust you, possibly, for the second one. They give you a chance to play out your second one.

DNA was my only gold rush. I regarded DNA as worth a gold rush.

Do things as soon as you can. If a decision needs to be made, make it. It gives you more time to change your mind.

The biggest advantage to believing in God is you don’t have to understand anything, no physics, no biology. I wanted to understand.

If I had been married earlier in life, I wouldn’t have seen the double helix. I would have been taking care of the kids on Saturday. On the other hand, I was lonely a lot of the time.

The division of the spoils between the victors will also provide employment for a powerful office, whose doorsteps the greedy adventurers and jealous concession hunters of twenty or thirty nations will crowd and defile.

So long as there is one [person] who seeks employment and cannot find it, the hours of work are too long.

During the period of capital moving from one employment to another, the profits on that to which capital is flowing will be relatively high, but will continue so no longer than till the requisite capital is obtained.

I conceive, therefore, that a somewhat comprehensive socialisation of investment will prove the means of securing an approximation to full employment.

Logic , like lyrical poetry , is no employment for the middle-aged.

Gold and silver, like other commodities, have an intrinsic value, which is not arbitrary, but is dependent on their scarcity, the quantity of labour bestowed in procuring them, and the value of the capital employed in the mines which produce them.

Employment is nature’s physician, and is essential to human happiness.

Could a man live by it, it were not unpleasant employment to be a poet.