“I play with microbes. There are, of course, many rules to this play…but when you have acquired knowledge and experience it is very pleasant to break the rules and to be able to find something nobody has thought of.”

One sometimes finds what one is not looking for.

Penicillin cures, but wine makes people happy.

Nature makes penicillin; I just found it.

It was astonishing that for some considerable distance around the mould growth the staphococcal colonies were undergoing lysis. What had formerly been a well-grown colony was now a faint shadow of its former self…I was sufficiently interested to pursue the subject.

One sometimes finds what one is not looking for. When I woke up just after dawn on Sept. 28, 1928, I certainly didn’t plan to revolutionize all medicine by discovering the world’s first antibiotic, or bacteria killer. But I guess that was exactly what I did.

Suggested remedy for the common cold: A good gulp of whiskey at bedtime-it’s not very scientific, but it helps.

Penicillin sat on a shelf for ten years while I was called a quack.

The unprepared mind cannot see the outstretched hand of opportunity.

If penicillin can cure those that are ill, Spanish sherry can bring the dead back to life.

It is the lone worker who makes the first advance in a subject: the details may be worked out by a team, but the prime idea is due to the enterprise, thought, and perception of an individual.

For the birth of something new, there has to be a happening. Newton saw an apple fall; James Watt watched a kettle boil; Roentgen fogged some photographic plates. And these people knew enough to translate ordinary happenings into something new.

(The discovery of penicillin) was a triumph of accident, a fortunate occurrence which happened while I was working on a purely academic bacteriological problem.

Everyone’s trying to reach the top. Tell me how far is it from the bottom.

I find meditative partnership with my horse, being one with another being is such as exhilarating experience

The feeling of awed wonder that science can give us is one of the highest experiences of which the human psyche is capable.

Your parents don’t teach you how to heal, experience does.

All the ups and downs you’ve experienced in your life were only preparing you for what’s to come.  

You experience a lot of new things by being silent.

I’d rather have a lot of talent and a little experience than a lot of experience and a little talent.

I grew up like a neglected weed – ignorant of liberty, having no experience of it.