“There is very little real liberty in the world; even those who seem freest are often the most tightly bound. Law, custom, public opinion, fear or shame make slaves of us all, as you will find when you try your experiment.”

He was the first, the only love her life, and in a nature like hers such passions take deep root and die-hard.

Some people seemed to get all sunshine, and some all shadow.

Where the heart is the mind works best.

In the books I read the sinners are always more interesting than the saints, and in real life good people are dismally dull. I’ve no desire to be wicked, but I do want to be happy. A short life and a gay one for me and I’m willing to pay for my pleasure if it is necessary.

I’d rather take coffee than compliments now.

Honesty is the best policy, in love as in law.

Don’t shut yourself up in a band box because you are a woman, but understand what is going on, and educate yourself to take part in the world’s work, for it all affects you and yours.

Love is a great beautifier.

Wild roses are fairest, and nature a better gardener than art.

Some books are so familiar that reading them is like being home again.

Marriage, they say, halves one’s rights and doubles one’s duties.

My book came out; and people began to think that topsy-turvy Louisa would amount to something after all.

Nothing is impossible to a determined woman.

It takes so little to make a child happy, that it is a pity in a world full of sunshine and pleasant things, that there should be any wistful faces, empty hands, or lonely little hearts.

Be comforted, dear soul! There is always light behind the clouds.

It takes very little fire to make a great deal of smoke nowadays, and notoriety is not real glory.

We must trust to nothing but facts: These are presented to us by Nature, and cannot deceive. We ought, in every instance, to submit our reasoning to the test of experiment, and never to search for truth but by the natural road of experiment and observation.

Experimenters are the shock troops of science.

In my experience most mathematicians are intellectually lazy and especially dislike reading experimental papers. He seemed to have very strong biological intuitions but unfortunately of negative sign.

The whole art of making experiments in chemistry is founded on the principle: we must always suppose an exact equality or equation between the principles of the body examined and those of the products of its analysis.

We are sometimes asked what the result would be if we put four +’s in one gene. To answer this my colleagues have recently put together not merely four but six +’s.

What I’m saying is, when different experiments give you the same result, it is no longer subject to your opinion. That’s the good thing about science: It’s true whether or not you believe in it. That’s why it works.

The language of experiment is more authoritative than any reasoning: facts can destroy our ratiocination—not vice versa.

Experimental confirmation of a prediction is merely a measurement. An experiment disproving a prediction is a discovery.